Is there a Way to Convert Scientific Paper PDFs to Neatly Formated?

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Is there a way to convert scientific paper pdfs to neatly formated epubs?

Converting pdf's to well-formatted epub is not easy particularly since pdf structure can be particularly difficult for a computer to figure out on it's own. For example, Calibre often fails for multi-column text such as scientific articles. That being said, there is a really good free program I found recently called Willus.com's K2pdfopt that can restructure a pdf into a single column (better for reading on small screens like smartphones). It does this by hunting through the original pdf and finding blocks of text/images that represent the flow of the document. This can be a great way to simplify your pdf and make it possible for programs like Calibre to easily build a neatly formatted epub document. In this way, it would be a 2-step process that can be easily automated in the end.

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I'm using this program so far on Caliber to turn my PDF's into a well-formatted pub document. The program finds and sorts the blocks of text and images relative to the main text or image sections. Once the process is complete it outputs a pub file that I can easily make into a book. Caliber can then be used to convert other documents into nice nicely formatted pub documents. But there's a little more to it than that. This process is not always easy to maintain or automate. For example, each time I convert one file into a pub I have to manually find/replace all the old lines.   That's a little difficult, but Caliber uses the searchable XML metadata as the source data for that. It means that I do not have to worry about manually finding those lines to be updated. It would be easy to create a separate software.